Our intestines are full of tiny creatures that help us digest our food, protect us from harmful interactions, and act as a link between our digestive system and brain. From bacteria and fungi to viruses, these microbial communities help maintain our ShipShape.
But when we drink medicine, we interrupt this strong run – And not just for a moment, a great new lesson is discovered. The effect of these drugs can be seen in some years.
In addition, it is not only antibiotics that cause this intestinal inflammation, but other common medications do.
Related: An Unusual Activity In Our GUTS Could Have Helped Our Brains Grow
“The effect of drug use has been underestimated,” the team led by Genomicist Oliver Aasmets from the University of Tartu in Estonia wrote in their paper.
“The effects of antibiotics, psychotics, antidepressics, proton pump inhibitors, and beta-blockers are found after several years of use.”
Bacterial culture was analyzed in human fat under scanning electron micron. (Steve GSchmeissiers/Science Photo Library/Getty Images)
Aasmets and his team investigated the records of 2,509 people who participated in the Estonia BioBank project.
Among the details, including a subset of 328 follow-ups, the researchers could see that stopping and starting certain medications changed the microbiomes of the patients. This suggests causar activity, the researchers explained.
Of the 186 drugs the group investigated, 167 (about 90 percent) were associated with changes in firoome fonseliome samples.
“Human-targeted drugs appear to reduce diversity by eliminating specific taxa,” explained Aasmets and team.
Benzodiazepines, commonly used for anxiety, have the same effect as broad-spectrum antibiotics, which are known to be very destructive to our internal environment.
In addition, not all benzodiazepines had the same effects. For example, Alprazolam (brand name XANAX) had a wider effect on gut microbe diversity than diazepam (brand name). This suggests that we may need to increase which drugs are not the best in a given situation, but also do less damage to our microbiomes.
These effects can also include.
“The more drugs are used, the stronger the effect on the microbiome,” the researchers wrote.
“We identified carver effects and additive effects.”
Win a $10,000 Space Coast Adventure Vacation
Previous studies in mice have suggested long-term antibiotic use can disrupt the mucosal lining, which may contribute to weight gain. The group urges more research to determine the effects of long-term exposure to various drug classes.
“Most microbiome studies only consider current medication, but our results show that past drug use can be just as important as it is a surprisingly powerful factor in explaining differences in other microbiomes,” said aasmets.
“We hope this encourages researchers and clinicians to consider the history of medicine when interpreting microbiome data.”
This research has been published internally Mystems.
